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Apheris Co-Folding Application

Predict the 3D structure of macromolecule complexes with an emphasis on protein–ligand, protein–protein, and antibody–antigen interfaces using OpenFold3 and Boltz-2.

Save time. Securely install OF3 and Boltz-2 locally with just one click

Support for data preparation


Benchmarking and model inference capabilities


Seamless integration into enterprise research stacks

Enjoy simple, local model deployment with security and privacy at its core at no cost.

Designed for scientists, the Apheris Co-Folding Application is built to supplement rather than replace existing internal pipelines. It's free of charge, runs entirely in local or private cloud environments and integrates with enterprise R&D stacks.

Documentation

Local deployment

Ensure full data control, security, and compliance through local deployment. Keep your sensitive data away from unrestricted public co-folding servers where you don’t control how your data is protected.

Data preparation

Streamline data preparation using built-in quality control and preprocessing tools for faster onboarding

Model inference

Run model inference with input validation and batch execution – either programmatically via API or manually through a user-friendly GUI.

Benchmarking

Evaluate model performance with detailed accuracy metrics, confidence scores, and 3D visualizations.

Enterprise integration & scaleability

Handle high-demand workloads across many users and models over multiple GPUs – compatible with any cloud provider and cost-efficient through on-demand GPU provisioning.

Try the Apheris Co-Folding Application, the all-in-one tool for benchmarking structure-based models like OpenFold3 and Boltz-2 on your data.

Join the waitlist, and we’ll let you know as soon as it’s live.